How does the CDC’s PulseNet system primarily track foodborne illnesses?
Answer
Using DNA fingerprinting of isolated bacteria
The CDC's PulseNet system functions based on the principles of molecular epidemiology. Its core mechanism involves collecting biological samples from sick individuals, isolating bacteria from those samples, and then performing DNA fingerprinting, which often involves whole-genome sequencing. This precise molecular data allows investigators to establish definitive links between seemingly disparate cases, confirming connections retrospectively after lab confirmation and sequencing protocols have been completed. This process contrasts sharply with proactive detection systems that aim to identify the initial cluster before sufficient samples are even available for molecular analysis.
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