Which historical figure developed the first successful vaccine against smallpox in 1796?
Answer
Edward Jenner
The history of vaccination predates modern platforms by centuries, with foundational steps being taken long ago. A pivotal moment occurred in 1796 when Edward Jenner successfully developed and demonstrated the first effective vaccine designed to protect against smallpox. This early achievement, along with practices such as variolation, established the fundamental necessity for organized immunization efforts, setting a historical precedent that informed later administrative programs like the World Health Organization's Expanded Programme on Immunization.

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