When did the term "digital biomarker" appear to crystallize and see an explosion in literature?
Answer
Early to mid-2010s.
Although the underlying technological precursors for remote monitoring have much deeper roots, the formal concept and terminology associated with the 'digital biomarker' solidified during a specific period. The early to mid-2010s marked the point when researchers and industry leaders recognized the substantial potential of smartphones and wearables to transition from simple fitness tracking tools into devices capable of generating validated clinical endpoints. This recognition spurred an increase in academic and industry publications dedicated to defining, classifying, and pushing these new measurement classes toward regulatory acceptance.
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