What key component of early CGM development relied on an enzyme such as glucose oxidase?
Answer
The electrochemical sensor designed to detect glucose levels.
The scientific foundation for accurate glucose measurement in CGMs hinges on the development of highly specific biosensors. A major hurdle overcome in establishing this foundation involved creating an electrochemical sensor capable of reliably detecting glucose concentration. This detection mechanism typically functions by employing an enzyme, such as glucose oxidase, which reacts specifically with glucose to produce a proportional electrical signal. This signal is then converted by the device's internal electronics into the numerical glucose reading the user observes.
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