During which initial stabilization period were early CGM readings often unreliable or requiring external confirmation?
Answer
The two-hour sensor warm-up period needed for equilibration with interstitial fluid.
Early Continuous Glucose Monitors required a distinct 'warm-up' phase following sensor insertion before reliable data could be obtained. This stabilization period was necessary because the sensor needed time to properly equilibrate and adjust to the surrounding interstitial fluid environment within the body. For these initial devices, this process often mandated approximately two hours during which the readings were considered unreliable or necessitated cross-checking with an external confirmation method, like a traditional fingerstick test, to ensure clinical validity.
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