What is a defining challenge associated with the distribution of orphan vaccines?

Answer

They often receive less funding for distribution infrastructure compared to blockbuster vaccines.

Orphan vaccines are those targeted at diseases that primarily affect poorer nations and lack the commercial incentive for mass-market investment. Because they are often produced for lower-income regions, they frequently lack the sustained global funding and infrastructure support that accompany blockbuster vaccines for diseases like polio or smallpox. This financial and logistical disparity forces health organizations to engage in specialized, iterative innovation, creating unique, low-volume, high-performance packaging solutions to ensure these vaccines remain potent without the benefit of large-scale supply chain investment.

What is a defining challenge associated with the distribution of orphan vaccines?
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